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tDCS

Transcranial direct current stimulation improves tinnitus perception and modulates cortical electrical activity in patients with tinnitus: A randomized clinical trial

https://www.sciencedirect.com/science/article/abs/pii/S0987705320300769?via%3Dihub

https://doi.org/10.1016/j.neucli.2020.07.002

https://pubmed.ncbi.nlm.nih.gov/32863109/

TITLE:
Transcranial direct current stimulation improves tinnitus perception and modulates cortical electrical activity in patients with tinnitus: A randomized clinical trial

ALTERNATIVE TITLE:
None

DATE:
Mon, 31 Aug 2020 06:00:00 -0400

AUTHORS:
Dayse da Silva Souza,Alexandre Alex Almeida,Suellen Marinho Dos Santos Andrade,Daniel Gomes da Silva Machado,Márcio Leitão,Tanit Ganz Sanchez,Marine Raquel Diniz da Rosa

SOURCE:
Neurophysiologie clinique = Clinical neurophysiology

DESCRIPTION:

CONCLUSIONS: These results demonstrate that tDCS modulates the EEG activity and alleviates tinnitus perception. This effect may be related to baseline EEG activity.

CONTENT:

Neurophysiol Clin. 2020 Aug 28:S0987-7053(20)30076-9. doi: 10.1016/j.neucli.2020.07.002. Online ahead of print.

ABSTRACT

OBJECTIVES: This study aims to determine whether transcranial direct current stimulation (tDCS): a) is effective in the treatment of tinnitus by decreasing its annoyance and severity; b) modulates the cortical electrical activity of such individuals.

METHODS: A double-blind, placebo-controlled clinical trial was conducted with 24 patients with tinnitus, randomized into two groups: Group 1 (n = 12) received anodal tDCS over the left temporoparietal area (LTA) and cathodal tDCS over the right dorsolateral prefrontal cortex (DLPFC) and Group 2 (n = 12) received placebo intervention. Tinnitus perception using a visual analog scale (VAS) and the Tinnitus Handicap Inventory (THI) questionnaire, in addition to electroencephalogram (EEG) was measured with eyes opened and closed at baseline and after the intervention. For the treatment, patients were subjected to five consecutive sessions of tDCS with the anodal electrode over the LTA and cathodal electrode over the right DLPFC (7 × 5 cm, 2 mA for 20 min). tDCS was turned off after 30 s in the sham group.

RESULTS: Active tDCS significantly improved tinnitus annoyance and severity. It was associated with decreased beta and theta EEG frequency bands with eyes opened and decreased alpha frequency with eyes closed. sLORETA identified changes in frequency bands in the frontal, temporoparietal, and limbic regions. Finally, there were negative correlations between baseline EEG frequency bands and tDCS-induced change in tinnitus annoyance and severity.

CONCLUSIONS: These results demonstrate that tDCS modulates the EEG activity and alleviates tinnitus perception. This effect may be related to baseline EEG activity.

PMID:32863109 | DOI:10.1016/j.neucli.2020.07.002

PUBMED ID:
pubmed:32863109

OTHER ID:
pmid:32863109,doi:10.1016/j.neucli.2020.07.002

PUBLICATION DATE:
Mon, 31 Aug 2020 06:00:00 -0400
2020-09-01

RETRIEVAL DATE :
08/31/20 06:45AM

LINK – PUBMED:
https://pubmed.ncbi.nlm.nih.gov/32863109/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1raUxiGThRUW-m52df5Bb_DZzfOiKEExmPo2D4RXGu6sfr6ozK&fc=20200430165258&ff=20200831064521&v=2.11.5

LINK – DOI:
https://doi.org/10.1016/j.neucli.2020.07.002

LINK – FULL TEXT:
Pending

NOTES:
None

Single session anodal, cathodal and placebo bifrontal tDCS for treatment of intractable chronic tinnitus: A randomized controlled clinical trial

https://www.brainstimjrnl.com/article/S1935-861X(18)30731-9/fulltext

https://www.sciencedirect.com/science/article/pii/S1935861X18307319

Single session anodal, cathodal and placebo bifrontal tDCS for treatment of intractable chronic tinnitus: A randomized controlled clinical trial
A. Yadollahpour, S. Rashidi, S. Jaberzade
165
DOI: https://doi.org/10.1016/j.brs.2018.12.312

Adjunctive Role of Bifrontal Transcranial Direct Current Stimulation in Distressed Patients with Severe Tinnitus

https://synapse.koreamed.org/DOIx.php?id=10.3346/jkms.2019.34.e19

https://www.ncbi.nlm.nih.gov/pubmed/30662385?dopt=Abstract

Adjunctive Role of Bifrontal Transcranial Direct Current Stimulation in Distressed Patients with Severe Tinnitus.

J Korean Med Sci

Related Articles

Adjunctive Role of Bifrontal Transcranial Direct Current Stimulation in Distressed Patients with Severe Tinnitus.

J Korean Med Sci. 2019 Jan 21;34(3):e19

Authors: Lee HY

Abstract

Background: This study assessed the therapeutic effect of adjunctive bifrontal transcranial direct current stimulation (tDCS) in patients with tinnitus.

Methods: Forty-four patients who visited our university hospital with a complaint of non-pulsatile subjective tinnitus in January through December 2016 were enrolled. All patients received directive counseling and sound therapy, such as a sound generator or hearing aids, and/or oral clonazepam. Patients who agreed to undergo additional bifrontal tDCS were classified as the study group (n = 26). For tDCS, 1.5 mA of direct current was applied to the prefrontal cortex with a 10-20 EEG system for 20 minutes per session.

Results: The Tinnitus Handicap Inventory (THI), Beck Depression Inventory, and Visual Analog Scale (VAS) scores decreased significantly after treatment (P < 0.001). Patients who had a moderate or catastrophic handicap were significantly more likely to respond favorably to bifrontal tDCS (P = 0.026). There was no correlation of number of tDCS sessions with change in the THI or VAS score (P > 0.05). Logistic regression analysis revealed that the initial THI score was independently associated with improvement in the THI. However, tDCS was not a significant determinant of recovery.

Conclusion: tDCS can be used as an adjunctive treatment in patients with severe tinnitus. Although tDCS did not decrease the loudness of tinnitus, it could alleviate the distress associated with the condition in some patients with a moderate or catastrophic handicap.

PMID: 30662385 [PubMed – in process]

PubMed:30662385

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